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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T12752 | RORγt Inverse agonist 3 | Others | |
RORγt Inverse agonist 3 is a potent, selective and orally active inverse agonist of RORγ(EC50s of 0.22 μM and 0.15 μM for hRORγ and RORγt (human IL-17 cells), respectively). | |||
T62622 | MRL-871 | ||
MRL-871 (compound 3) is a potent isotretinoin receptor-related orphan receptor γt (RORγt) inverse agonist (IC50: 264 nM).MRL-871 has a specific isoxazole chemotype and is effective in reducing IL-17a mRNA production in E... |